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Hypertension current issue
Endothelial Nitric Oxide Synthase Polymorphism rs3918226 Associated With Hypertension Does Not Affect Plasma Nitrite Levels in Healthy Subjects [Letters to the Editor]
Luizon, M. R., Metzger, I. F., Lacchini, R., Tanus-Santos, J. E. Wed, 16 May 2012 13:20:19 -0700
Response to Endothelial Nitric Oxide Synthase Polymorphism rs3918226 Associated With Hypertension Does Not Affect Plasma Nitrite Levels in Healthy Subjects [Letters to the Editor]
Salvi, E., Cusi, D., on behalf of the HYPERGENES Consortium Wed, 16 May 2012 13:20:19 -0700
Fructose Likely Does Have a Role in Hypertension [Letters to the Editor]
Madero, M., Lozada, L. G. S., Johnson, R. J. Wed, 16 May 2012 13:20:19 -0700
Arteriosclerosis, Thrombosis, and Vascular Biology current issue
Development of a Magnetic Resonance Imaging Protocol for the Characterization of Atherosclerotic Plaque by Using Vascular Cell Adhesion Molecule-1 and Apoptosis-Targeted Ultrasmall Superparamagnetic Iron Oxide Derivatives [Integrative Physiology/Experimental Medicine]
Burtea, C., Ballet, S., Laurent, S., Rousseaux, O., Dencausse, A., Gonzalez, W., Port, M., Corot, C., Elst, L. V., Muller, R. N. Wed, 16 May 2012 13:36:39 -0700
Objective— Acute ischemic events are often caused by the disruption of lipid-rich plaques, which are frequently not angiographically visible. Vascular cell adhesion molecule-1 and apoptotic cell-targeted peptides studied during our previous work were conjugated to ultrasmall superparamagnetic iron oxide (USPIO) (USPIO-R832 for vascular cell adhesion molecule-1 targeting; USPIO-R826 for apoptosis targeting) and assessed by magnetic resonance imaging. Methods and Results— Apolipoprotein E knockout mice were injected with 0.1 mmol Fe/kg body weight and were imaged on a 4.7-T Bruker magnetic resonance imaging until 24 hours after contrast agent administration. Aortic samples were then harvested and examined by histochemistry, and the magnetic resonance images and histological micrographs were analyzed with ImageJ software. The plaques enhanced by USPIO-R832 contained macrophages concentrated in the cap and a large necrotic core, whereas USPIO-R826 produced a negative enhancement of plaques rich in macrophages and neutral fats concentrated inside the plaque. Both USPIO derivatives colocalized with their target on histological sections and were able to detect plaques with a vulnerable morphology, but each one is detecting a specific environment. Conclusion— Our vascular cell adhesion molecule-1 and apoptotic cell targeted USPIO derivatives seem to be highly promising tools for atherosclerosis imaging contributing to the detection of vulnerable plaques. They are able to attain their target in low doses and as fast as 30 minutes after administration.
Correction [Correction]
Wed, 16 May 2012 13:36:39 -0700
Summing Up [Editorial]
Fisher, E. A. Wed, 16 May 2012 13:36:39 -0700
Circulation Research current issue
The Future of Optical Mapping is Bright: RE: Review on: "Optical Imaging of Voltage and Calcium in Cardiac Cells and Tissues" by Herron, Lee, and Jalife [Letter to the Editor]
Efimov, I., Salama, G. Thu, 10 May 2012 13:01:38 -0700
Cthrc1 Is a Novel Inhibitor of Transforming Growth Factor-{superscript 2} Signaling and Neointimal Lesion Formation: Correction [Correction]
Thu, 10 May 2012 13:01:38 -0700
In This Issue [In This Issue]
Thu, 10 May 2012 13:01:38 -0700
Hypertension current issue
Endothelial Nitric Oxide Synthase Polymorphism rs3918226 Associated With Hypertension Does Not Affect Plasma Nitrite Levels in Healthy Subjects [Letters to the Editor]
Luizon, M. R., Metzger, I. F., Lacchini, R., Tanus-Santos, J. E. Wed, 16 May 2012 13:20:19 -0700
Response to Endothelial Nitric Oxide Synthase Polymorphism rs3918226 Associated With Hypertension Does Not Affect Plasma Nitrite Levels in Healthy Subjects [Letters to the Editor]
Salvi, E., Cusi, D., on behalf of the HYPERGENES Consortium Wed, 16 May 2012 13:20:19 -0700
Fructose Likely Does Have a Role in Hypertension [Letters to the Editor]
Madero, M., Lozada, L. G. S., Johnson, R. J. Wed, 16 May 2012 13:20:19 -0700
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Endothelial Nitric Oxide Synthase Polymorphism rs3918226 Associated With Hypertension Does Not Affect Plasma Nitrite Levels in Healthy Subjects [Letters to the Editor]
Luizon, M. R., Metzger, I. F., Lacchini, R., Tanus-Santos, J. E. Wed, 16 May 2012 13:20:19 -0700
Response to Endothelial Nitric Oxide Synthase Polymorphism rs3918226 Associated With Hypertension Does Not Affect Plasma Nitrite Levels in Healthy Subjects [Letters to the Editor]
Salvi, E., Cusi, D., on behalf of the HYPERGENES Consortium Wed, 16 May 2012 13:20:19 -0700
Fructose Likely Does Have a Role in Hypertension [Letters to the Editor]
Madero, M., Lozada, L. G. S., Johnson, R. J. Wed, 16 May 2012 13:20:19 -0700
Arteriosclerosis, Thrombosis, and Vascular Biology current issue
Development of a Magnetic Resonance Imaging Protocol for the Characterization of Atherosclerotic Plaque by Using Vascular Cell Adhesion Molecule-1 and Apoptosis-Targeted Ultrasmall Superparamagnetic Iron Oxide Derivatives [Integrative Physiology/Experimental Medicine]
Burtea, C., Ballet, S., Laurent, S., Rousseaux, O., Dencausse, A., Gonzalez, W., Port, M., Corot, C., Elst, L. V., Muller, R. N. Wed, 16 May 2012 13:36:39 -0700
Objective— Acute ischemic events are often caused by the disruption of lipid-rich plaques, which are frequently not angiographically visible. Vascular cell adhesion molecule-1 and apoptotic cell-targeted peptides studied during our previous work were conjugated to ultrasmall superparamagnetic iron oxide (USPIO) (USPIO-R832 for vascular cell adhesion molecule-1 targeting; USPIO-R826 for apoptosis targeting) and assessed by magnetic resonance imaging. Methods and Results— Apolipoprotein E knockout mice were injected with 0.1 mmol Fe/kg body weight and were imaged on a 4.7-T Bruker magnetic resonance imaging until 24 hours after contrast agent administration. Aortic samples were then harvested and examined by histochemistry, and the magnetic resonance images and histological micrographs were analyzed with ImageJ software. The plaques enhanced by USPIO-R832 contained macrophages concentrated in the cap and a large necrotic core, whereas USPIO-R826 produced a negative enhancement of plaques rich in macrophages and neutral fats concentrated inside the plaque. Both USPIO derivatives colocalized with their target on histological sections and were able to detect plaques with a vulnerable morphology, but each one is detecting a specific environment. Conclusion— Our vascular cell adhesion molecule-1 and apoptotic cell targeted USPIO derivatives seem to be highly promising tools for atherosclerosis imaging contributing to the detection of vulnerable plaques. They are able to attain their target in low doses and as fast as 30 minutes after administration.
Correction [Correction]
Wed, 16 May 2012 13:36:39 -0700
Summing Up [Editorial]
Fisher, E. A. Wed, 16 May 2012 13:36:39 -0700
Circulation Research current issue
The Future of Optical Mapping is Bright: RE: Review on: "Optical Imaging of Voltage and Calcium in Cardiac Cells and Tissues" by Herron, Lee, and Jalife [Letter to the Editor]
Efimov, I., Salama, G. Thu, 10 May 2012 13:01:38 -0700
Cthrc1 Is a Novel Inhibitor of Transforming Growth Factor-{superscript 2} Signaling and Neointimal Lesion Formation: Correction [Correction]
Thu, 10 May 2012 13:01:38 -0700
In This Issue [In This Issue]
Thu, 10 May 2012 13:01:38 -0700
Hypertension current issue
Endothelial Nitric Oxide Synthase Polymorphism rs3918226 Associated With Hypertension Does Not Affect Plasma Nitrite Levels in Healthy Subjects [Letters to the Editor]
Luizon, M. R., Metzger, I. F., Lacchini, R., Tanus-Santos, J. E. Wed, 16 May 2012 13:20:19 -0700
Response to Endothelial Nitric Oxide Synthase Polymorphism rs3918226 Associated With Hypertension Does Not Affect Plasma Nitrite Levels in Healthy Subjects [Letters to the Editor]
Salvi, E., Cusi, D., on behalf of the HYPERGENES Consortium Wed, 16 May 2012 13:20:19 -0700
Fructose Likely Does Have a Role in Hypertension [Letters to the Editor]
Madero, M., Lozada, L. G. S., Johnson, R. J. Wed, 16 May 2012 13:20:19 -0700
Sites:
of Cardiology: Web-based publication covering topics submitted by the medical community. Features case reports, editorials, images and peer reviewed articles.American Heart Journal: A monthly publication for cardiologists and general practice physicians. Includes clinical trial data, key findings from cardiovascular meetings and treatment cost-effectiveness.
Blood Pressure Monitoring: Provides access to full-text and online-only content, features and services, author submission materials and title-specific information.
Cardiology Clinics: Publication that focuses on a single topic per issue. Features reviews providing information on current diagnosis and treatment methods.
Cardiology in Review: Features reviews of the pathogenesis, diagnosis, clinical course and treatment of cardiovascular disorders. Includes author guidelines, editorial board and subscription information.
Cardiology in the Young: Bi-monthly publication focusing on issues of heart disease acquired in childhood. Includes original articles, editorials and continuing medical education papers.
Circulation: Weekly publication from the American Heart Association. Includes peer-reviewed reports on clinical and laboratory research and archives available from 1965 to present.
Circulation Research: Presents results of bench studies with subcategories including molecular medicine, cell biology and integrative physiology.
Coronary Artery Disease: Features articles on coronary artery disease with a clinical emphasis. Includes observational studies, clinical trials, and advances in laboratory research.
Current Atherosclerosis Reports: Literature review journal covering the latest research, clinical studies, and pharmacologic advances. Requires subscription.
Current Controlled Trials in Cardiovascular Medicine: Publishes clinical trial protocols, papers reporting interim and final results and original research.
Current Opinion in Cardiology: Bi-monthly resource featuring reviews and editorials on developments in valvular heart disease treatment, transplantation and pediatrics.
E-chocardiography Journal: An online publication from the University of Medicine and Dentistry, New Jersey. Includes articles, sample images, auscultation essays and an e-mail discussion group.
European Heart Journal: International peer-reviewed journal with research articles, technical evaluations, and reviews.
European Heart Journal Supplements: Supplements to the European Heart Journal, an international, peer-reviewed journal dealing with cardiovascular medicine.
European Journal of Echocardiography: Official publication of the European Association of Echocardiography. Features original peer-reviewed articles, technical evaluations, case reports and guest editorials.
European Society of Cardiology Journals: From this site, discover how to access content, subscribe and submit articles to each of the 7 official ESC journals.
Expert Review of Cardiovascular Therapy: Discusses the clinical applications of new medicines, therapeutic agents and diagnostics in this field.
Heart: Heart, a peer review journal for health professionals and researchers in all areas of cardiology
Heart Disease: Focuses on strategies for the prevention and management of disease. Includes articles on new therapeutics, surgical approaches and alternative medicine.
Heart Journal: Monthly web-based publication from Cairo University. Includes clinical cases, ECG discussion and review articles. [English and Arabic]
Heart Surgery Forum: The Heart Surgery Forum is an online peer-reviewed journal in Cardiothoracic Surgery offering scientific articles, multimedia presentations, discussion boards, news, announcements and more.
Hypertension: Monthly publication by the American Heart Association focusing on blood pressure regulation and pathophysiological mechanisms underlying hypertensive diseases. Includes peer-reviewed reports, articles and editorials.
Images in Paediatric Cardiology: On-line, peer-reviewed, pediatric, cardiology, journal. Home page.
Indian Pacing and Electrophysiology Journal: Indian Pacing and Electrophysiology Journal
Journal of Cardiovascular Risk: Addresses the causes and prevention of cardiovascular disease, as well as rehabilitation and exercise physiology. Includes original papers, editorials and clinical practices.
Journal of Clinical and Basic Cardiology: Austrian publication featuring original papers describing current research, observational studies and clinical trials. [Articles in English]
Journal of Endovascular Therapy: Welcome to the Journal of Endovascular Therapy (formerly Journal of Endovascular Surgery), a peer-reviewed online medical journal dedicated to peripheral vascular disease interventions. The Journal, an official publication of the International Society of Endovascular Specialists, features bim...
Journal of Interesting Electrocardiogram: resource center for electrocardiograms and electrocardiography
Journal of the American College of Cardiology: Includes original peer-reviewed clinical and experimental reports, new diagnostic techniques, clinical reviews and editorial commentary.
Journal of the Renin-Angiotensin-Aldosterone System (JRAAS): The Journal of the Renin-Angiotensin-Aldosterone System (JRAAS) provides the only scientific journal devoted exclusively to these developments. It includes: Original research on these peptide systems, clinical research reports on the blockade of the RAAS, results of clinical trials of drugs inhib...
Journal Watch Cardiology: Summaries and commentary of cardiology medical journal articles covering topics such as coronary artery disease and hypertension.
Nature Clinical Practice Cardiovascular Medicine: Nature Clinical Practice Cardiovascular Medicine will deliver timely interpretations of key research developments, translating the latest findings into clinical practice. Our Editor-in-Chief and international Advisory Board will ensure comprehensive coverage of topical issues throughout the year,...
Pediatric Cardiology Today: Monthly newsletter written by physicians, available in print or as PDF files online. Provides information on patient therapy, training opportunities and products and services.
Progress in Pediatric Cardiology: Presenting information and experienced opinion to aid in understanding and managing cardiovascular diseases in children.
Stroke: Journal of the American Stroke Association. Free searchable table of contents and abstracts from current and past issues as well as e-mail alerts. Full-text access by subscription only.
Texas Heart Institute Journal: The Texas Heart Institute Journal is published quarterly by the Texas Heart Institute, Houston, Texas.
The Journal of Hypertension: Official monthly journal of the European Society of Hypertension and International Society of Hypertension. Full articles available online.
